Vapen: de sterfgevallen, ziekten en controverses in het afgelopen jaar – CNET


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E-cigarette manufacturers hoping to stay on the market must submit a premarket tobacco product application to the FDA as part of the agency’s evolving regulation of the vaping industry.

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In recent weeks, there’s been a surge of reports about people ending up in the hospital because of lung issues, seizures and other health concerns after vaping — and seven people have died. It’s clear we’re just starting to understand all the dangers of vaping.

E-cigarettes hit the US market about a decade ago, touted as a safer alternative to traditional tobacco cigarettes. However, they didn’t really gain any traction until 2015, when Juul Labs (then part of Pax Labs) debuted its discreet USB-size vaporizer and quickly became the industry leader.

The result was a spike in e-cigarette use, especially among young adults, a segment of the population that, until then, had been using fewer tobacco products, according to the Centers for Disease Control and Prevention. In 2016, the Food and Drug Administration finalized a rule extending its authority to regulate all tobacco products, including e-cigarettes, the repercussions of which are still playing out today.

Below, we go through what’s happened over the past year as health officials and the vaping industry try to adapt within this rapidly changing regulatory landscape.

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Sept. 12, 2018 — FDA calls teen vaping an “epidemic”

Dr. Scott Gottlieb, the FDA commissioner at the time, issues a statement calling teen vaping an “epidemic” and urges the e-cigarette industry to address the problem or risk having their flavored products pulled from the market.

Sept. 31, 2018 — FDA inspectors seize documents from Juul Labs HQ

The FDA conducted an unannounced inspection of Juul Labs’ San Francisco headquarters, seeking more information about the company’s sales and marketing practices. Inspectors collected “over a thousand pages of documents,” according to the agency.

Nov. 18, 2018 — Juul Labs shuts down social media accounts

After the FDA expresses concern that Juul is luring in underage users, the company shuts down Facebook and Instagram accounts, and limits its Twitter presence to “non-promotional communications only.”

Tobacco Free Campus

The University of California, San Francisco, was ahead of the curve. It’s been a smoke- and tobacco-free campus since Aug. 1, 2017.

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March 13, 2019 — FDA restricts sale of flavored tobacco products

FDA issues new guidelines restricting the sale of most flavored tobacco products, including e-cigarettes, at convenience stores, gas stations and pharmacies. The FDA also asks that all e-cigarette manufacturers submit applications showing their products meet current regulations by Aug. 8, 2021.

March 27, 2019 — Health experts sue FDA over delay of e-cigarette review

Seven public health and medical groups and several pediatricians file suit against the FDA for not following proper requirements when the agency gave e-cigarette companies more time to submit their products for review.

April 3, 2019 — FDA announces investigation into potential link between seizures and vaping

The FDA notifies the public that it has received reports of people experiencing a seizure following the use of e-cigarettes.

June 25, 2019 — San Francisco bans e-cigarettes

San Francisco, home to Juul’s headquarters, becomes the first city in the US to ban the sale of e-cigarettes.

July 12, 2019 —E-cigarette marketing application submission deadline set

A US District Court judge in Maryland gave e-cigarette companies until May 12, 2020, to submit premarket tobacco applications to the FDA for approval.

July 23, 2019 — FDA launches anti-vaping ads to combat teen vaping

The FDA launches new anti-vaping commercials as part of The Real Cost, the agency’s nearly $60 million smoking prevention campaign. In the TV ads, a street magician uses tricks to educate teens on the risks of using e-cigarettes.

July 24, 2019 — Facebook, Instagram restrict e-cigarette content

Facebook issues a new policy that will restrict sales of and limit content related to alcohol and tobacco products, including e-cigarettes, across Facebook and Instagram.

July 26, 2019 — WHO issues global tobacco epidemic report

In a report, the World Health Organization calls for more research and regulation of e-cigarettes and specifically names Juul as one of the new industry players that “continue to subvert tobacco control.”

Aug. 7, 2019 — FDA says it’s received 127 reports of vaping-related seizures

FDA releases a statement saying it’s now received a total of 127 reports of seizure or other neurological symptoms, such as fainting or tremors, that occurred after vaping between 2010 and 2019.

Aug. 14, 2019 — Vaping industry group sues FDA

The Vapor Technology Association, which represents hundreds of vaping companies, files suit against the FDA to delay regulators’ review of the e-cigarettes currently on the market.

Aug. 16, 2019 — Investors still bullish on Juul Labs

Juul Labs raised another $325 million from investors, despite growing health and legal concerns, according to regulatory filings.

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Juul Labs was founded by former smokers with the goal of eliminating cigarettes, according to the company’s mission statement.

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Aug. 17, 2019 — CDC opens probe into vaping-related lung disease

State and federal health officials team up to explore whether e-cigarettes caused severe pulmonary issues in 153 people (and counting).

Aug. 19, 2019 — Juul Labs sued over marketing practices

A 19-year-old Juul user sues the company for targeting minors and using deceptive marketing practices, saying the practices led to his nicotine addiction. The lawsuit also names tobacco giant Philip Morris and its parent company Altria, a Juul investor.

Aug. 19, 2019 — Health officials report more than 150 people have been hospitalized

State and federal health officials report that 153 people — many of them young adults — across 16 states have been treated for respiratory issues that occurred after vaping.

Aug. 20, 2019 — Juul Labs leaves Vapor Technology Association

Six days after the VTA issued a lawsuit against the FDA, Juul Labs announces that it won’t renew its membership to the industry group, citing differences on “critical policy issues.”

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The CDC says “e-cigarette products should not be used by youth, young adults, pregnant women, as well as adults who do not currently use tobacco products.”

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Aug. 23, 2019 — Illinois reports a patient dying after vaping

The Illinois Department of Public Health said a person who had “recently vaped and was hospitalized with severe respiratory illness” had died. The death may be the first tied to vaping in the US, according to the Associated Press.

Aug. 28, 2019 — Juul CEO says respiratory illness cases are ‘worrisome’

Juul CEO Kevin Burns calls the recent string of lung illnesses potentially linked to vaping “worrisome” and urges nonsmokers to avoid using Juul. “If there was any indication that there was an adverse health condition related to our product, I think we’d take very swift action,” Burns said in a CBS This Morning interview.

Aug. 29, 2019 — FTC launches an investigation into Juul’s marketing practices

The Federal Trade Commission has launched an investigation into whether Juul practiced deceptive marketing, including targeting minors and may seek monetary damages, according to a report from The Wall Street Journal.

Aug. 30, 2019 — CDC: Don’t buy vaping products off the street, and don’t modify them

The Centers for Disease Control and Prevention “took the unusual step” of issuing recommendations regarding vaping and e-cigarette products, The New York Times reported. The CDC’s vaping recommendations cover the general public, clinicians and public health officials. Among the advice for the public: “Anyone who uses e-cigarette products should not buy these products off the street (e.g., e-cigarette products with THC, other cannabinoids) and should not modify e-cigarette products or add any substances to these products that are not intended by the manufacturer.” The CDC also said, as it had done previously, that “e-cigarette products should not be used by youth, young adults, pregnant women, as well as adults who do not currently use tobacco products.”

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In early September, the CDC released a statement about its investigations and said no single product is linked to all cases of lung disease. 

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Sept. 4, 2019 — A second vaping-related death

Severe lung disease linked to vaping took another life, according to The New York Times. The unidentified person was hospitalized after vaping THC using a product bought at an Oregon recreational marijuana shop, the Times said. The patient was “otherwise healthy and quickly became very ill,” a public health physician and lead investigator in the case told the paper. 

Sept. 5, 2019 — Indiana reports vaping-related death 

A third life was claimed by severe lung injury related to vaping, The Wall Street Journal confirmed. After news of the individual’s death, federal health authorities urged people to stop using e-cigarette products while they investigate about 450 cases of the mysterious illness in 33 states.

Sept. 6, 2019 — Two more deaths and CDC warning

Health officials in Minnesota confirmed that a 65-year-old person died in August after a long hospitalization from severe lung injury. The person had a history of underlying lung disease, but the lung injury was associated with vaping illicit THC products. The lung injury progressed to other conditions, ABC 5 reported on Friday. The Minnesota Department of Health told the station that the state has had 17 patients to date who’ve been classified as confirmed or possible cases. An additional 15 cases are under investigation.

The first death in Los Angeles county related to vaping was also reported the same day by ABC 7. The county has reported 12 cases “of vaping-associated pulmonary injury” to date, according to its Department of Public Health. 

The CDC also released a statement about its investigations and said no single product is linked to all cases of lung disease. Many of the patients reported recent use of products containing THC while some reported using products with both THC and nicotine. A smaller group said they used nicotine only. 

Illinois Sen. Dick Durbin tweeted a letter to Ned Sharpless, acting commissioner for the US Food and Drug Administration, demanding action. Durbin said the FDA should send letters to all schools in America warning them of health consequences related to vaping. He also called on the agency to ban e-cigarette flavors other than tobacco and ban e-cigarette devices that haven’t been approved by the FDA.  

“If Dr. Sharpless doesn’t take action in the next 10 days, I plan to call for his resignation. Enough is enough,” Durbin tweeted

The vaping epidemic has now reached the point where multiple people have died and over 450 have been hospitalized, but @FDACommissioner is sitting on his hands. If Dr. Sharpless doesn’t take action in the next 10 days, I plan to call for his resignation. Enough is enough. pic.twitter.com/6yXbu3TxSn

— Senator Dick Durbin (@SenatorDurbin) September 6, 2019

Sept. 9, 2019 — FDA calls out Juul for claiming vaping is safer than other tobacco products

The FDA has raised more concerns about Juul over some questionable marketing that suggested that Juul’s vaporizer is safer than other tobacco products. What’s worse, high school students testified before Congress claiming that a company rep vertelde hen dat Juul “volkomen veilig” is. P>

september 12, 2019 – Er verschijnen foto’s met ernstige longschade , Juul blijft advertenties ondanks FDA waarschuwing

Een verzameling foto’s verkregen door Business Insider van artsen en onderzoekers illustreert wat wordt verondersteld de ernstige effecten van longschade door dampen . De afbeeldingen bevatten die van een tiener uit Californië die een operatie heeft ondergaan om een ​​blaar te verwijderen die zijn longen ineenzakte nadat hij een cannabisdamp gebruikte die hij tijdens een concert had gekocht. Andere foto’s illustreren patronen opgemerkt door onderzoekers, waaronder ontsteking, schade aan de longblaasjes (of de luchtzakken van de longen) en vetdeeltjes in longweefsels. De in het artikel geciteerde chirurgen zeiden dat ze niet konden bevestigen dat de verwondingen en ziekten zeker veroorzaakt waren door vapen.

Ondanks een waarschuwingsbrief van de Amerikaanse Food and Drug Administration vorige week, vertelde een woordvoerder van Juul CNBC het bedrijf zal zijn advertentiecampagne” Make the Switch “blijven uitvoeren , waardoor vapen wordt beschouwd als een veiliger alternatief voor sigaretten. Het bedrijf moet de FDA-goedkeuring verkrijgen voordat het beweert dat een product veiliger is dan sigaretten, maar heeft geen aanvraag voor een dergelijke goedkeuring ingediend, aldus CNBC. P>

september 16, 2019 – Drie bevestigde gevallen van ernstige longziekte gerelateerd aan vapen in Washington

De Washington State Department of Health bevestigde twee nieuwe gevallen van ernstige longziekte in verband met vapen, wat het totale aantal bevestigde gevallen opleverde over de gehele staat tot drie. Van de twee nieuwe gevallen is één patiënt in de tienerjaren en de andere in de twintig. Alle drie bevestigde gevallen meldden vóór het begin van hun ziekte vapen, maar de afdeling heeft nog geen gemeenschappelijk product, hulpmiddel of additief onder de drie geïdentificeerd, hoewel onderzoeken nog gaande zijn.

“De symptomen van deze patiënten komen overeen met wat de Centra voor ziektebestrijding en preventie hebben alle nationale en lokale gezondheidsjurisdicties gevraagd op te letten met betrekking tot het landelijke onderzoek naar deze zaak, “zei Washington State Health Officer Kathy Lofy in een persbericht. “Dit is nu een staatsbrede uitbraak.” P>

september 19, 2019 – Door de FDA aangekondigde criminele sonde voor vapen aangekondigd als ziekten oplopen tot 530

Gezondheidsfunctionarissen van de Centers for Disease Control zeiden dat het aantal gevallen van vapengerelateerde longziekten is gestegen tot 530 in 38 staten. Zoals gemeld door De Washington Post , de Food and Drug Administration onthulde een strafrechtelijk onderzoek naar de uitbraak. Tot nu toe zijn zeven mensen aan de ziekte overleden. De FDA heeft meer dan 150 monsters verzameld van patiënten in het hele land en analyseert deze nu op de aanwezigheid van snijmiddelen en andere stoffen. P>

september 20, 2019 – Walmart stopt met de verkoop van e-sigaretten

Onder vermelding van “regelgevingscomplexiteit” en “onzekerheid” rond e-sigaretten, Walmart zei dat het zal stoppen met de verkoop van de producten, volgens een nieuw rapport van CNBC. Eerder dit jaar heeft het bedrijf verhoogde de vereiste leeftijd om tabaksproducten te kopen naar 21 en stopte de verkoop van fruit en dessert nicotine smaken. P>

september 24, 2019 – Californië waarschuwt voor” plotselinge longschade “

Het California Department of Public Health publiceerde een gezondheidsadvies dat burgers waarschuwt voor de “dreigende risico’s voor de volksgezondheid die verbonden zijn aan het vapen van elk product.” Het zei dat het meldingen heeft ontvangen van 90 mensen in Californië met een geschiedenis van vapen die in het ziekenhuis werden opgenomen “voor ernstige ademhalingsproblemen en longschade.”

Twee mensen zijn ook gestorven in Californië, zei de afdeling volksgezondheid van de staat. Het advies voegde eraan toe dat iedereen moet stoppen met vapen “ongeacht de stof of bron.” Als mensen doorgaan met vapen, zouden ze nooit een vapenproduct moeten wijzigen of er een op straat kopen, zei het.

Vapen lijkt ‘plotselinge longschade’ te veroorzaken, zei de CDPH. Symptomen die verband kunnen houden met vapen zijn hoesten, pijn op de borst, ademhalingsmoeilijkheden, misselijkheid, braken, diarree, buikpijn, vermoeidheid, koorts en gewichtsverlies.

De afdeling volksgezondheid van de staat zei dat het werkt met de CDC, FDA, andere gezondheidsafdelingen en zorgaanbieders die onderzoeken wat er in vapen is dat mensen ziek maakt.

sept. 25, 2019 – Juul CEO treedt terug als vapenbedrijf stopt met adverteren in de VS

Kevin Burns, die Juul mede-oprichtte, wordt vervangen door KC Crosthwaite – een directeur voor tabaksbedrijf Altria. Juul zei ook dat het alle uitzendingen, gedrukte en digitale advertenties in de VS zou opschorten en beloofde de Trump-regering “af te zien van lobbyen” over haar voorstel om gearomatiseerde e-sigaretten te verbieden.


Opmerking: de informatie in dit artikel is alleen voor educatieve en informatieve doeleinden en is niet bedoeld als gezondheids- of medisch advies. Raadpleeg altijd een arts of andere gekwalificeerde zorgverlener voor vragen die u heeft over een medische aandoening of gezondheidsdoelstellingen.

Alison DeNisco Rayome, Rae Hodge, Corinne Reichert en Sean Keane van CNET hebben bijgedragen aan dit rapport.

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